Evaluation of biopsy specimens of skin and genital warts in pathology department of Shahid Sadoughi Hospital in Yazd during the years 2012 to 2020

Background and Aim: Warts are one of the most common lesions sent to the pathology department. Genital warts are at risk for malignancy transformation, especially in the cervix. By recognizing these lesions as soon as possible, especially in the genital areas, malignancies can be prevented with prompt treatment. Methods: In this retrospective and descriptive study, demographic information (age and sex) and anatomical location of the lesion were extracted from patients' pathology records according to a pre-arranged checklist. Data were entered into SPSS version 22 and then statistical analysis was performed using descriptive tests or mean±standard deviation, or analytical statistical tests (with 95% confidence, interval). P<0.05 was considered statistically significant. Results: A total of 267 patients were included in the study. 143 patients (53.6%) were women. The age range of patients was 2 to 80 years (31.3+15.5). The locatin of warts were on limbs in 150 (56.2%), genital area in 82 (30.7%), head and neck in 25 (9.4%) and trunk in 10 (3.7%) patients. The distribution frequency of lesions on the limbs was higher in males (P=0.01). Warts in the genital area, trunk and neck were more common in females (P=0.02). Conclusion: Genital warts were more common in female patients and on the other hand, warts on limbs were more common in males. Therefore, any lesion with wart characteristics in women should be taken seriously.